PROJECTS FUNDED BY MW

PROJECTS FUNDED BY MEAGAN’S WALK

Meagan’s Walk is dedicated to funding research and initiatives that:

Bring the top brain tumour experts all over the world together to share knowledge and to collaborate on research.
Uncover when and how genetic mutations arise to cause brain tumours in children.
Identify new, less toxic treatments for children with brain tumours, helping them live healthier lives.

FUNDED THIS YEAR

Meagan’s Walk Seed Operating Grant

Unravelling the DNA Damage Response Pathway in High Risk Ependymoma

Principal Investigator:Dr. Vijay Ramaswamy

Investigating the switch between quiescence and proliferation in the stem cell compartment of sonic hedgehog subgroup medulloblastoma

Principal Investigator: Dr. Peter Dirks

Methionine deprivation as a therapeutic strategy for diffuse intrinsic pontine glioma

led by Dr. Cynthia Hawkins

Splicing regulation of tumour suppressor activity in pediatric brain cancer

Principal Investigator: Dr. Jane McGlade

Application of next generation genomic tools to identify predictors of success and failure for infant brain tumour therapy

led by Dr. Annie Huang

Deciphering mechanical heterogeneity and its regulators for brain tumour therapeutics

Principal Investigator: Dr. Xi Huang

BTRC Pediatric Biologics Repository and Database for Brain Tumours

Principal Investigator: Dr. James Rutka

Partnered Funding Projects

Epigenetic alterations define lethal CMP-positive ependymomas of infancy

Principal investigators: Dr. James Rutka and Dr. Michael Taylor

Funders: Meagan’s Walk and the Pediatric Brain Tumor Foundation of America

Partnered Funding Projects

Epigenetic alterations define lethal CMP-positive ependymomas of infancy

Principal investigators: Dr. James Rutka and Dr. Michael Taylor

Funders: Meagan’s Walk and the Pediatric Brain Tumor Foundation of America

National Collaborative Seed Grant

ReRad: A Phase II Study of Re-Irradiation of Treatment of Progressive Diuse Intrinsic Pontine Glioma with the Canadian Paediatric Brain Tumour Consortium of the Alberta Children’s Hospital and University of Calgary.

Health Related Quality of Life in Patients Diagnosed with Diuse Intrinsic Pontine Glioma and their Caregivers in collaboration with Dr. Fiona Schulte of the Alberta Children’s Hospital

The Role of RNA Stress Granules in GBM Treatment Resistance in collaboration with Dr. Weeks from Dalhousie University in Nova Scotia

The study of Medulloblastoma subgroup 3 Development in collaboration with Dr. David Eisenstat from the University of Alberta